Hoerndli Lab publications
Doser RL, Knight KM, Deihl EW, Hoerndli FJ. Activity-dependent mitochondrial ROS signaling regulates recruitment of glutamate receptors to synapses. Elife. 2024 Mar 14;13:e92376. doi: 10.7554/eLife.92376. PMID: 38483244
Stetak AL, Grenal T, Lenninger Z, Knight KM, Doser RL, Hoerndli FJ. A necessary role for PKC-2 and TPA-1 in olfactory memory and synaptic AMPAR trafficking in C. elegans. J Neurosci. 2024 Jan 18:e1120232024. doi: 10.1523/JNEUROSCI.1120-23.2024. Epub ahead of print. PMID: 38238075.
Hoerndli FJ, Kurshan P.T, and Anggono V. (2024). Editorial for Frontiers in Cellular Neuroscience and Cellular neurophysiology Topic:” The Role of Trafficking in Synaptic Development, Maintenance, and Plasticity”.
Doser R, Knight KM, Deihl E, Hoerndli F. Subcellular Imaging of Neuronal Calcium Handling In Vivo. J Vis Exp. 2023 Mar 17;(193). doi: 10.3791/64928. PMID: 37010315.
Nakul Sridhar, Apresio Kefin Fajrial, Rachel Doser, Frederic Hoerndli*, Xiaoyun Ding* (2022). Surface Acoustic Wave Integrated Microfluidics for Repetitive and Reversible Temporary Immobilization of C. elegans. Lab Chip. 2022 Dec 6;22(24):4882-4893. PMID: 36377422. * Shared senior author. https://doi.org/10.1039/d2lc00737A
Pierce D, Doser RL, Dunlap J, Valdez M, Pulford BE and Hoerndli FJ. (2022). A dual role for LAR/PTP-3 enables transport and synaptic recruitment of AMPARs necessary for memory. bioRxiv 2022. https://doi.org/10.1101/2022.08.11.503694
Hoerndli FJ, Brockie PJ, Wang R, Mellem JE, Kallarackal A, Doser RL, Pierce DM, Madsen DM, Maricq AV. MAPK signaling and a mobile scaffold complex regulate AMPA receptor transport to modulate synaptic strength. Cell Rep. 2022 Mar 29;38(13):110577. doi: 10.1016/j.celrep.2022.110577. PMID: 35354038. https://doi.org/10.1016/j.celrep.2022.110577
Doser, RL; Hoerndli, FJ (2022). Decreased Reactive Oxygen Species Signaling Alters Glutamate Receptor Transport to Synapses in C. elegans AVA Neurons. microPublication Biology. https://micropublication.org/journals/biology/micropub-biology-000528
Doser RL., Amberg GC., and Hoerndli FJ., (2020) Reactive Oxygen Species Modulate Activity-Dependent
AMPA Receptor Transport in C. elegans. Jneurosci. 40(39):7405–7420. https://doi.org/10.1523/JNEUROSCI.0902-20.2020
Hoerndli F.J., A. Kallarackal, and A.V. Maricq (2015) Mobile AMPARs are required for synaptic plasticity. Channels(Austin) 9:230-2.
Hoerndli F.J., R. Wang, J.E. Mellem, A. Kallarackal, P.J. Brockie, C. Thacker, D.M. Madsen and A.V. Maricq (2015) Neuronal activity and CaMKII regulate kinesin-mediated transport of synaptic AMPARs. Neuron 86: 1-18. (Cited in Faculty 1000) (Google Scholar Citations: 28)
Hoerndli F.J.*, D.A. Maxfield*, P.J. Brockie, J.E. Mellem, E. Jensen, R. Wang, D.M. Madsen and A.V. Maricq (2013) Kinesin-1 regulates synaptic strength by mediating the delivery, removal and redistribution of AMPA receptors. Neuron 80:1421-37. Feature article (*, co-first authors) (Cited in Faculty 1000) (Google Scholar Citations: 44)
Brockie, P.J., M. Jensen, J. Mellem, E. Johnson, R. Wang, D.A. Maxfield, F.J. Hoerndli, D.M. Madsen and A.V. Maricq (2013) Cornichons control ER export of AMPA receptors to regulate synaptic excitability. Neuron 80:129-42. (Google Scholar Citations: 35)
Wang, R., J.E. Mellem, M. Jensen, P.J. Brockie, C.S. Walker, F.J. Hoerndli, D.M. Madsen and A.V. Maricq (2012) The SOL-2/Neto auxiliary protein modulates the function of AMPA-subtype ionotropic glutamate receptors. Neuron 75:838-50. (Google Scholar Citations: 29)
Jensen, M., F.J. Hoerndli, P.J. Brockie, R. Wang, E. Johnson, D. Maxfield, M.M. Francis, D.M. Madsen and A.V. Maricq (2012) Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system. Cell 149:173-87. (Google Scholar Citations: 79)
Stetak, A., F. Hörndli, A.V. Maricq, S. van den Heuvel and A. Hajnal (2009) Neuron-specific regulation of associative learning and memory by MAGI-1 in C. elegans. PLoS One 4:e6019. (Google Scholar Citations: 44)
Hoerndli, F.J., M. Walser, E. Fröhli Hoier, D. de Quervain, A. Papassotiropoulos and A. Hajnal (2009) A conserved function of C. elegans CASY-1 calsyntenin in associative learning. PLoS One 4:e4880. (Google Scholar Citations: 39)
Hoerndli, F.J., S. Pelech, A. Papassotiropoulos and J. Götz (2007) Abeta treatment and P301L tau expression in an Alzheimer’s disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. Eur J Neurosci 26:60-72. (Google Scholar Citations: 34)
Huentelman, M.J., A. Papassotiropoulos, D.W. Craig, F.J. Hoerndli, J.V. Pearson, K.D. Huynh, J. Corneveaux, J. Hänggi, C.R. Modardori, A. Buchmann, E.M. Reiman, K. Henke, D.J. de Quervain and D.A. Stephan (2007) Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance. Mol Genet 16:1469-77. (Google Scholar Citations: 62)
Papassotiropoulos, A., D.A. Stephan, M.J. Huentelman, F.J. Hoerndli, D.W. Craig, J.V. Pearson, K.D. Huynh, F. Brunner, J. Corneveaux, D. Osborne, M.A. Wollmer, A. Aerni, D. Coluccia, J. Hänggi, C.R. Mondadori, A. Buchmann, E.M. Reiman, R.J. Caselli, K. Henke and D.J. de Quervain (2006) Common Kibra alleles are associated with human memory performance. Science 314:475-78. (Google Scholar Citations: 373)
Hoerndli, F.J., M. Toigo, A. Schild and J. Götz (2004) Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reaction. Anal Biochem 335:30-41. (Google Scholar Citations: 74)
Chen, F., M.A. Wollmer, F. Hoerndli, G. Münch, B. Kuhla, E.I. Rogaev, M. Tsolaki, A. Papassotiropoulos and J. Götz (2004) Role for glyoxalase I in Alzheimer’s disease. Proc Natl Acad Sci USA 101:7687-92. (Google Scholar Citations: 158)
Ferrari, A., F. Hoerndli, T. Baechi, R.M. Nitsch and J Götz (2003) beta-Amyloid induces paired helical filament-like tau filaments in tissue culture. J Biol Chem 278:40162-68. (Google Scholar Citations: 167)
Streffer, J.R., A. Papassotiropoulos, P. Kurosinski, A. Signorell, M.A. Wollmer, M. Tsolaki, V. Iakovidou, F. Hörndli, J. Bosset, J. Götz, R.M. Nitsch and C. Hock (2003) Saitohin gene is not associated with Alzheimer's disease. J Neurol Neurosurg Psychiatry 74:362-63. (Google Scholar Citations: 24)
Reviews
Doser RL., and Hoerndli FJ., (2021) Regulation of neuronal excitability by reactive oxygen species and calcium signaling: Insights into brain aging. Current Research in Neurobiology. (Graphical Review). 2 (2021) 100012. https://doi.org/10.1016/j.crneur.2021.100012
Götz, J., D. David, F. Hoerndli, Y.D. Ke, N. Schonrock, A. Wiesner, T. Fath, L. Bokhari, Y.A. Lim, N. Deters and L.M. Ittner (2008) Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response. Neurodegener Dis 179-81. (Google Scholar Citations: 10)
Hoerndli, F., D.C. David and J. Götz (2005) Functional genomics meets neurodegenerative disorders. Part II: Application and data integration. Prog Neurobiol 76:169-88. (Google Scholar Citations: 40)
David, D.C., F. Hoerndli and J. Götz (2005) Functional genomics meets neurodegenerative disorders. Part I: Transcriptomic and proteomic technology. Prog Neurobiol 76:153-68. (Google Scholar Citations: 36)
Götz, J., J.R. Streffer, D. David, A. Schild, F. Hoerndli, L. Pennanen, P. Kurosinski and F. Chen (2004) Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy. Mol Psychiatry 9:664-83. (Google Scholar Citations: 260)
Götz, J., A. Schild, F. Hoerndli and L. Pennanen (2004) Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models. Int J Dev Neurosci 22:453-65.